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Managing FD

A Tyramine Avoidance Diet

 

As reported in the article, New Discovery, some autonomic crises may be preventable by avoiding certain dietary triggers, including a compound called tyramine. FD patients may wish to access the accumulated wisdom of other patient populations, most notably, those who suffer from migraines, and those who take a class of antidepressant drugs known as MAO inhibitors, or MAOIs.  People on MAOIs are always warned by their doctors to avoid tyramine because it can cause hypertensive crises, which have symptoms that are very familiar to the autonomic crises experienced by those with FD: elevated blood pressure and heart rate, excessive sweating, and vomiting. Similarly, some migraine sufferers experience autonomic crises very similar to FD crises (in addition to head pain and visual auras) when they eat certain foods.

 

Internet-based research using the search term “tyramine” can be very useful for compiling a tyramine-free or low-tyramine diet. For the convenience of our readers, we are publishing some dietary guidelines here as well.  Generally speaking, any food made of protein contains the tyramine precursor, the amino acid tyrosine. As tyrosine breaks down, tyramine levels increase, so the longer a food is stored, the greater the possible quantity of tyramine. Therefore, protein based foods should always be as fresh as possible, and leftovers from those foods should not be eaten.

 

The following foods are known to contain high levels of tyramine and should be avoided: ales and beers (including non-alcoholic), burgundy and chianti wine (including non-alcoholic), sherry, and vermouth; breads made with cheeses and meats or yeast extracts, high-yeast breads; aged cheeses (the cheese closest to the rind has the most tyramine); eggplant, red plums, banana peels and overripe bananas, fava bean pods, Italian or broad green beans, kim chee (fermented cabbage), lentils, lima beans, sauerkraut, overripe fruit; aged, dried, or cured meats, dried or pickled fish, meat jerky, leftover meats, liver, meat extracts, salami or dry sausage, salted, smoked, pickled, or canned meat or fish, shrimp paste; meat tenderizers; brewer’s yeast, broth with yeast, commercial gravies, unpasteurized milk products, crackers made with cheese, homemade yeast breads, marmite, vegemite, and other yeast spreads, miso (fermented soybean paste), soy and teriyaki sauces, yeast extracts, and tofu if more than a few days old. Monosodium glutamate (MSG) can cause a tyramine-like reaction so should also be avoided. Many prepared foods, such as canned soups, contain yeast products or MSG, so labels should be read carefully.

 

The following foods should be eaten with caution and moderation; negative reactions should be carefully watched for: bouillon; distilled liquor, some wines; commercial breads without or low in yeast and sourdough bread, yogurt, avocados (not overly ripe), Chinese pea pods, raspberries,  papaya, passion fruit, spinach, tomatoes, dried fruits, citrus and pineapple; peanuts and other nuts and seeds; and chocolate products.

 

Tyramine content can vary depending on processing method, age, and amount of fermentation, ripeness, or contamination. For example, game meats are often aged before they are cooked, making them unsafe. Foods that typically have small amounts of tyramine can become foods with high levels as they are stored over time. Protein-based foods that are stored should be viewed with suspicion, including luncheon or deli meats, protein extracts used in dietary supplements, gelatin, and some condiments and seasonings.

 

 

 

 

 

 

 

 

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